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George Church, a professor of genetics at Harvard and creator of direct genome sequencing, claims that editing the human genome should be utilized as long as it is proven to be safe and beneficial in trials. Church believes that trials should start “focus initially on fixing the most deadly, currently incurable genetic diseases in newborns”. Church is suggesting that trials begin with children who have, for example, Tay-Sachs disease, which causes an early death around age 4. If they have a small chance of living, then he believes that it at least gives them a chance of survival. Instead of beginning trials off with something like HIV that can be controlled using ART, trials with something like Tay Sachs, where they die so young, will give researchers the opportunity to improve techniques and see if using CRISPR to cure diseases can work and possibly work for HIV in the future. 

Dolores Garcia-Arocena, a technical information scientist at The Jackson Laboratory, believes that targeting T cells using CRISPR technology will be an effective method to remove HIV from the infected T cells. She says, "scientists are coming closer to beating AIDS with a combination of powerful antiretroviral therapies". While she understands that there are still many hoops to go through in order for HIV/ AIDS to be cured, it is a step in the right direction with great potential. 

Dolores Garcia-Arocena

Step in The Right Direction

Focus on Deadliest Diseases

George Church

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